Intellectual disability and autism in propionic acidemia: a biomarker-behavioral investigation implicating dysregulated mitochondrial biology

Introduction   Propionic acidemia (PA) is a rare genetic disorder that affects how the body breaks down certain amino acids and fatty acids. People with PA have high levels of toxic substances in their blood and urine, which can cause serious health problems. PA can also affect the brain and behavior, leading to intellectual disability … Read more

Role of autonomic, nociceptive, and limbic brainstem nuclei in core autism features

Introduction   Autism is a developmental disorder that affects how people communicate, interact, and behave. Researchers have long wondered what causes autism and how it affects the brain. One area of the brain that has received less attention is the brainstem, which is located at the base of the skull and connects the spinal cord … Read more

Is There a Bias Towards Males in the Diagnosis of Autism? A Systematic Review and Meta-Analysis

Introduction   Autism is a neurodevelopmental condition that affects communication and social interaction, as well as behaviours and interests. Autism is more common in males than in females, but some studies suggest that females are more likely to be misdiagnosed or underdiagnosed. This could be due to differences in the way autism manifests in different … Read more

Age effects on autism heritability and etiological stability of autistic traits

Introduction   Autism is a lifelong condition that affects how people communicate and interact with others. Autism is also associated with a range of behavioral and cognitive traits, such as social difficulties, repetitive behaviors, and sensory sensitivities. These traits can vary in severity and frequency across individuals and across the lifespan.   But what causes … Read more

Pain detection through facial expressions in children with autism using deep learning

Introduction   Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects how people communicate and interact with others. Children with ASD may have difficulty expressing their emotions, especially pain, which can lead to poor pain management and unnecessary suffering. In this blog post, I will summarize a recent research paper that proposes a novel … Read more

How Gut Bacteria Affect Children with Autism and Stress

Introduction   Autism spectrum disorder (ASD) is a developmental condition that affects how people communicate and interact with others. Many children with ASD also have gastrointestinal (GI) problems, such as constipation, diarrhea, or abdominal pain. These GI problems can cause stress and worsen the behavioral symptoms of ASD. But what causes these GI problems in … Read more

Parent Coaching to Target Language Outcomes for Chinese Learning Autistic Preschoolers: A Preliminary Study

Introduction   Autism spectrum disorder (ASD) is a developmental condition that affects social communication and behavior. Children with ASD often have language delays or impairments, which can affect their academic and social outcomes. One way to support language development in children with ASD is to provide parent-mediated interventions, which involve training parents to use specific … Read more

Autism spectrum disorder diagnosis across cultures: Are diagnoses equivalent?

Introduction   Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects how people communicate and interact with others. ASD is diagnosed based on behavioral criteria, such as social communication difficulties, restricted interests, and repetitive behaviors. However, these criteria may not capture the full diversity and complexity of ASD across different cultures and contexts. In … Read more

Stigma on Children with Autism

Introduction   Autism is a developmental disorder that affects communication, social, and behavioral aspects of children. Children with autism often face stigma and discrimination from society, which can affect their self-esteem, mental health, and quality of life. This literature review aims to explore the sources, forms, and impacts of stigma on children with autism and … Read more

Enhanced group level dorsolateral prefrontal cortex subregion parcellation through functional connectivity-based distance-constrained spectral clustering with application to autism spectrum disorder | Cerebral Cortex

introduction   The brain is a complex organ that consists of many regions with different functions and connections. One of these regions is the dorsolateral prefrontal cortex (DLPFC), which is involved in cognitive and behavioral control, such as working memory, attention, decision making, and social communication. The DLPFC is also a crucial target for interventions … Read more